New Patients Please Call 646-506-3745

  • Welcome to Esco Drug Inc.

    Welcome to Esco Drug Inc.

    With Quality Care, You Can Lift Up The Universe

  • Diabetes Care

    Diabetes Care

    Let us help you understand and manage your diabetes

  • Durable Medical Equipment

    Durable Medical Equipment

    Available for purchase and rental

  • Free Daily Delivery

    Free Daily Delivery

    We offer free delivery within a 20-mile radius

  • Immunizations


    We offer a variety of vaccines to keep you healthy

  • Long Term Care

    Long Term Care

    Medications and consultant services to long-term care facilities

  • Medication Savings

    Medication Savings

    Your health shouldn't have to break the bank

  • Medication Therapy Management

    Medication Therapy Management

    We can help you manage your medications and health conditions

  • Medicare Open Enrollment

    Medicare Open Enrollment

    Let us help you choose a plan during the medicare open enrollment period

  • Health Screenings

    Health Screenings

    Get info about your health without having to make a trip to the doctor

Refill a Prescription

We fill new and existing prescriptions in-store, by phone, online, and with our mobile app.

Refill Now

Transfer a Prescription

Transfer your prescriptions to our pharmacy using our simple and secure online transfer form.

Transfer Now

Contact Us

Visit us in store or get in touch with a member of our pharmacy staff. We're always happy to assist you.

Get in Touch


Esco Services Update

As of 2/8/21, most services are back, with the exception of Western Union. Please refer to the information below for any hours related to the services we provide.

1. Store Retail Hours [Updated 2/8/21]

  • Esco Will Be Open
  • Mon-Sat: 8:30 a.m. - 8 p.m.
  • Sun: 10 a.m. - 6 p.m.

2. Services: Adjusted [Updated 2/8/21]

  • All Services Listed Below Are From 10 a.m. - 5p.m.
  • DMV Vision Test
  • Lottery
  • Notary (Saturday Only)
  • Pepper Spray
  • Vaccines (Non-COVID)
  • Copy and Fax

3. Store Policy | Keep Clean

When entering Esco, you will be prompt to use our sanitizer to prevent spreading of germs, bacteria, and viruses. Keeping yourself safe keeps Esco and every customer afterwards safe!

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Our Services

Your One Stop Shop

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Dispill® Pill Packaging

Our custom medication packaging organizes and color-codes prescriptions by date and time.


Easy Prescription Filling

We fill new and existing prescriptions in-store, by phone, online, and with our mobile app.

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Free Delivery

We offer free local delivery daily within a 20-mile radius of the pharmacy for your convenience.


Medication Savings

Our pharmacists work with you to coordinate benefits and find financial assistance.

Download Our Free App.
Your health information in one place.

✓ Refill 24/7 »
✓ Set Reminders »
✓ Save on Medications »

Read Our Patient Reviews


Francis T.

"I've lived in Hell’s Kitchen since 2004 and I don’t use any other pharmacy. Nicest people possible, and they're family to many of us in the neighborhood. Support the local small independent businesses!"


Laura K.

"I have gone to Esco for years. Danny, the pharmacist, and his team go above and beyond when it comes to customer service, whether it's regarding a prescription or special ordering a hand soap or lotion. And they deliver! A treasure in the heart of Hell's Kitchen."


Andrew M.

"Independently owned, local pharmacy. Friendly and professional. Excellent service. Great to support a locally owned, small, independent business. Old school NYC!"

Learn About Us »

Esco Drug Inc. combines high quality products with personalized care. Our staff is happy to help you with any questions you may have.

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Explore Our Health News »

Check out our weekly health news blog, or subscribe to our newsletter and receive updates on health articles, promotions, and specials.

Welcome to Esco Drug Inc.

Find Services »

We offer a wide variety of services including conventional prescription filling, compounding, medical equipment, and immunizations.


We'd Love To Hear From You

  • At Esco Drug Inc., we’re committed to helping you live a healthier life. Our pharmacy staff would be happy to help you with any questions you may have.