New Patients Please Call 646-506-3745
Refill a Prescription
We fill new and existing prescriptions in-store, by phone, online, and with our mobile app.
Transfer a Prescription
Transfer your prescriptions to our pharmacy using our simple and secure online transfer form.
Contact Us
Visit us in store or get in touch with a member of our pharmacy staff. We're always happy to assist you.

Esco Services Update
As of 2/8/21, most services are back, with the exception of Western Union. Please refer to the information below for any hours related to the services we provide.
1. Store Retail Hours [Updated 2/8/21]
- Esco Will Be Open
- Mon-Sat: 8:30 a.m. - 8 p.m.
- Sun: 10 a.m. - 6 p.m.
2. Services: Adjusted [Updated 2/8/21]
- All Services Listed Below Are From 10 a.m. - 5p.m.
- DMV Vision Test
- Lottery
- Notary
- Pepper Spray
- Vaccines (Non-COVID)
3. Store Policy | Keep Clean
When entering Esco, you will be prompt to use our sanitizer to prevent spreading of germs, bacteria, and viruses. Keeping yourself safe keeps Esco and every customer afterwards safe!
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Our Services
Your One Stop Shop
Dispill® Pill Packaging
Our custom medication packaging organizes and color-codes prescriptions by date and time.
Easy Prescription Filling
We fill new and existing prescriptions in-store, by phone, online, and with our mobile app.
Free Delivery
We offer free local delivery daily within a 20-mile radius of the pharmacy for your convenience.
Medication Savings
Our pharmacists work with you to coordinate benefits and find financial assistance.

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Read Our Patient Reviews

Francis T.
"I've lived in Hell’s Kitchen since 2004 and I don’t use any other pharmacy. Nicest people possible, and they're family to many of us in the neighborhood. Support the local small independent businesses!"

Laura K.
"I have gone to Esco for years. Danny, the pharmacist, and his team go above and beyond when it comes to customer service, whether it's regarding a prescription or special ordering a hand soap or lotion. And they deliver! A treasure in the heart of Hell's Kitchen."

Andrew M.
"Independently owned, local pharmacy. Friendly and professional. Excellent service. Great to support a locally owned, small, independent business. Old school NYC!"
Learn About Us »
Esco Drug Inc. combines high quality products with personalized care. Our staff is happy to help you with any questions you may have.
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Check out our weekly health news blog, or subscribe to our newsletter and receive updates on health articles, promotions, and specials.
Find Services »
We offer a wide variety of services including conventional prescription filling, compounding, medical equipment, and immunizations.

We'd Love To Hear From You
At Esco Drug Inc., we’re committed to helping you live a healthier life. Our pharmacy staff would be happy to help you with any questions you may have.
- SEND AN EMAIL
New Patients: 646-506-3745
Current Patients: 212-246-8169
Fax: 212-265-7364